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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7af10abc90cf804ded823313046c74c4c4249b2b3ae3d3fba760ac78e8da13' 
  AND token = 'PvT6nQVXaFnHlclG6k0slkI/fPohO4dB7tSzMaH/iCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}