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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0dc91cd5c9fab891c4cd65ff3d70149283220eda4e7308149fb9beddc7fdaf' 
  AND token = 'JAZ6zW5Y19c5K2NqEPYiqqII/q2ZdZS4rrCXRExWu6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}