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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd06069057a898018dced70f9b5e2df018ef4f4c8e7a31bd6f6ba33e66f5f88b4' 
  AND token = 'gr1T72xGoMwLWI02B0vsICVCmRpooHcdcAKIXppTtis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}