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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '333a9d44d703b28d1de24f1a7fae44992be67d20b9eb2e95e164921423ec8e90' 
  AND token = 'jRUfFuS7Ce0ETK3lTIiXPYCyNbB7jvsuu4Hz6hUa+Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}