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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03e0fbe309e161f9530954acc4cdf23a6c8f87f04162bcb950e9eabd8c511834' 
  AND token = 'T44qJZ6d7dokL2y8uPTfZUlMRH2tIlztlBnFOGWbfDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}