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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5622a654995550d63b6fe67a76b635608f3f4d454e741a9fb57d90a1f0ebfd59' 
  AND token = '2fFINf/t1uAOsfd+tlSNwTB7k9lxxdkPTEAJqcU+zLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}