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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e962ea56a544f2d437c1dfbc7960cf1487bc8f88053c03e3d8a358ad1bfa3c04' 
  AND token = 'eM7Lt1tPGY71/sA0SpbmMEjG6IAkilrf6Qsm1XbH9ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}