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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1894db9ce346629cbeb19e6a3b55ede64158a4c9fe9aac45a9744522024afa2' 
  AND token = 'i0pawOMnrVDPG9HwaRh6YMlL4Shggsv2OUEzeGtTdBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}