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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19a70878aae6d26eb0579ff0e51e382d87232c5595fc0048501681509cfcde19' 
  AND token = 'QGVVK21qwuvxyEt2Oy00DqEEdp+NN3ergDfVOR+9VRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}