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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b3555ad50ea3b14f9f82e456cf054f8ebae15c00b80f9977dcdfd523a1d1ba' 
  AND token = '3qhCwFVrX3gkAfbzc6CdaFqrB9Azsu436q3s3qfilEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}