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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4206d7b1755e495c521bc88a7ea0780d9ab8a5b6b9e0fb604f1f3c6313edca71' 
  AND token = 'WpJoQzkycJCOb6dbHgb3pI4jefl3A+xwooe20yh0Ef4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}