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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f6fbd1a77662111eb56fb80552de77757f6afb7cf1daca452e6c213c18853d9' 
  AND token = 'gsLdCOUNJ6MMo/9h5/ZXJ6rTAybHThxD/3uh9Ek1Qh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}