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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c269d8818f4fd6e63ed730a4d34b1f0a915945664b11c71e851487655eab9a76' 
  AND token = 'T+02fDMib1jJKGhXPgFnC6GAf0MmRgqRiSz0bq8Y64I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}