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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09780c06c267e1a5e7cd1fe5f955cd3a89f494b9b7e7d0c82761fbd438978187' 
  AND token = 'Ur7k9zdOStmN+xYzLL3GcY/nbWGgK/2KWA7Hqr3Z4HY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}