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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33db632ae496d44f287071562d000f9ab47a3ee50fd88fba63c01df62148c338' 
  AND token = '78B9Vy0Q4mjGDgP1TajS4ONX/CV8OXUc0PC1KdDvD/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}