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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b331caa333e2513ef2c23fc746db5427337f4de5d2e6fa7aad88cbb1d0e021a0' 
  AND token = 'UQ1qc1Ypw3pfmXMukpRZ1DRci57TdkmR/y7LbNdSA7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}