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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f790d911cce20dd0137b4b3db2729aae213360fe3f74c79a34f4634e59bec959' 
  AND token = 'wmyDZcf5iClyOdHgJwJJMda8x+hkEYDi+WxgF1BVvJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}