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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ba189f8d43e83e71e16e6974b366f785aff1e36821818b68427848f49ed7390' 
  AND token = 'ecYCW4FD/fEWuxMiFYp1JAV9ikD0ck3yZxjtB1v0w1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}