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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b860de917a5dd833ea9e81feefad5d5b0207b02b5e54c030635d23bff51655' 
  AND token = '8zDh8VF9uYT4fTyn8FBLKsCCgZmNEeimMTFCFz47AXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}