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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7a60e2b7405248729afbc27c26fc89d4662f3ce5c88e8e088e3ac64c9365e61' 
  AND token = 'niQcW8YgN6L1l5dXd+iIPwCiEM/qtFBnHrSN/eMJQZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}