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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e62f4db2ccc93799456ad9bdc552222570819d3c204bc03dc9fb32ed8d0b83e3' 
  AND token = 'LfMxIsfcMVR0gFiV0k3rEXUs0YdDpfxODBSPhpYgCPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}