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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9e9cf2088fc995ae4baad89d4355279df03fe34802255f5b06821e8ac7854bf' 
  AND token = 'JQkCFbvblZcwAOW4gbE3F+9z5TCrRneOLnuCdBkaUkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}