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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe4245abec9b646ce07629e40c54be230e1261af56f000b6c57f6fef30320222' 
  AND token = 'tYjpm3knryx3GORVH1ofwLTjc2Tz89+lLWpB9k3ESdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}