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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2633e7e74bc09674eae4bab7f9beee122790dc54adab9a2887dd066abf8e2e46' 
  AND token = 'p1thkG4RrqiMJ4MuANAxSqLC9QTwytglu58Q9/1Qc3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}