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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd46efb7542f69120e4757234c3434cbb8c8cd891223293bc99491e9de8a0dd33' 
  AND token = 'SDHKt2XiOwmAF/mhRx43V7XyXJey9re/yLZGS6gClJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}