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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00a23493f344e6810ab6e70eb6a905beaf331bc75e5bc8da2699afc96e83a4b' 
  AND token = 'nBWhQVKLAUdk0zEjWT6VSLtfhyWj2WWbRj52drgiSxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}