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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0ad93bfa83c0472b91b4ac55024ae46c1245812d16dd4ee5939eb2fd651ef7' 
  AND token = '2+AJ0uml+d/KD5v2cVmu5/JS7Wjq4MIp2Izr83mRkNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}