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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1357a22efface15395e5b67509ad6bc1848b01547f58e68ea34d730238a7cbb2' 
  AND token = 'Y1PWRSoS+pdH++lTBW4t0a/47jsiihJMb7UtaI0cIq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}