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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4541ad3e51229af73f588112b4f4b54ead6b295238ca7aa9b71b3e6b8a69c673' 
  AND token = 'KNm7bsdWrHgJC49grHavE9CqYKHIPQbD6JoKOO9TH00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}