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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195d0105423fd20f298c74a7d7e5133fe06ba25c242cdd1d8bd4c051bc6db806' 
  AND token = 'Ag6CtWlcLd/MbijWkOG6KboViNU4BEe9KJwqIGwNXTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}