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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed8f302a659f61a06396094cf385b5fae489e9bd22332a1a83636d32b65ef79' 
  AND token = 'kgcJxuHi7HYRBaFZru6yxU+yuhA3FhZ27BPrcZvO5KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}