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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2f3242679f031b2110e44b1311f7029f5d1063ec2c831ea47e00a6bf1125b94' 
  AND token = '2MDkpZJL3PfPQaBuQxzP8HviMKBI7CKQNpcWs9ZRt18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}