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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b32873e952bc5684d82b5b4e6d21cc24b6f02ed21e34223d9f0b7bb4a3e3e1ba' 
  AND token = 'UmNq8ObKQR6LO9wUaX3YWVNTjmPUKnjrcaLT4vLXwlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}