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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef13b591e7552999bc4384fcfb6002e58a4f4cc9e6189c99340d15e8b36052cd' 
  AND token = 'wqlGCnX2//8J3OH4Z21vyEpwOYtsZ8i45SHhDbG7UGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}