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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a300d70d76064bc5d35c14b1741228f34b0e5545c06340729c623956b8bfba3a' 
  AND token = 'M0FPVVtuUWHEU3tBeNh5PwI31qBhnBMO87FcOqKzcmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}