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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce9d04cefd12b105581fe2c99caad61ed0a232d149e06535619b711f0e6bf2b7' 
  AND token = 'loTrNNv0JCcJI7XYWV2cnv6b0On94rseYghnEmlWqzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}