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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d8fd96304b923a9bb8be01e9580f1e679d5c9424df9111185440a688258d864' 
  AND token = 'qD9jrl8mWtPboRZbFd4DxYTkqlGfC/jm8rgusniM6Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}