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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5396bd288bfe38cf4e2ec682bdb5a7bdfe48f738945849d5f1003067fc409607' 
  AND token = 'DdNvubXbO5mzTPZtFV7oeoy7RWR7bCW8t81MgOrVVgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}