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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53ef12266e0ed2f6b8c33253a5808f21c727a3765411943e18c794a2df926b2' 
  AND token = 'qbkTHzpN0qDBU8ZPmE53xWT62KGWrgUZw0rY8tu9dog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}