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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a9b0c80e061dba1acb2ac73fdb73c8ab7adc646a23b619b92af4f582abfc1af' 
  AND token = '3mlIU3xOm9OwZN6edlTH1GpNP5OPgGuGyqXJsvGFIwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}