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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e3ff0c9e42a7b808c3a572977661ab185dcfbe36d4c4368487a15452055535' 
  AND token = 'UInt1pdPXX7Nb/nDUoPqy2ogCNfqg9eWB+bgC49Xsi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}