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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80232117be186e758a3a11a3dd7a5d172d04b70ad98f548d145756a7c7c87b96' 
  AND token = 'YFot7w0LXOtdk1Un1ACkhRs4HYC644yt5+BP0EpV1Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}