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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc177002d5e5488f1a04fb08c9c149d9373060b1289bd3ca92e55c7695d0d0b' 
  AND token = 'PdcbTWMDE06INzwErR9kQOeXbzyGEdtn5rCVu/YoSDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}