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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '720d98d378b40bef266bdf0ccf81b3381cff1e82ffbd597f2a556f6575147919' 
  AND token = 'HUlWufPqWIc+DkeNW3+ySTMkiQag9AU+nFLgwHZ+5Fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}