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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f032eea0deda00368ab3f5b229739cc27e55be0f6f1bf003b9f691bdfe37b37' 
  AND token = 'a2+9VHKBLdxbn8ZDLsw251O3uGQURZ4yV9MRaj9C5no=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}