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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4225e0c037235ef0feed69c08f4151a139921b3aa3255fe38a15fc1d209f9aa2' 
  AND token = 'H8DZ2wnH/J44XHy88ukFFOZjCfRbbps0ebobwKCcNLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}