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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e5a2d845e5465de4aa57e9bf593040833cf035d71049a43a343b8ffb4844252' 
  AND token = 'saSdgf3TTuStXq4l54THAtA6UnUbteHp1n4GMjNY4bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}