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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a220be55ee53095000ca166b23d6389390e9486cfe15d392bacd6ee1e02e9d5' 
  AND token = '2bsaBbp5bgNx2rpx8Qa79xG2DLhegJJ9XsN4Is2Jgks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}