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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81379df693608ddf5de9793a5cbb8a98620bb95218fa988b158f7c9055074cc2' 
  AND token = '0vHmgFeUxjO+QCcn4oW/6ExzENcdyzHeTwQCf3x4AqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}