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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8848278a43b57f85dd1c56720761f24e1e8e836d84e44db98dc7c77d6c9aa24' 
  AND token = 'Bo+eYLKQ6dxVIVjtqF6nUc88XLj6szxINBk2QpuXJy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}